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Effect of Radiation Therapy on Atelectasis from Lung Cancer
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È«¼º¾ð(Hong Seong-Eon) - °æÈñ´ëÇб³ ÀÇ°ú´ëÇÐ Ä¡·á¹æ»ç¼±°úÇб³½Ç
È«¿µ±â(Hong Young-Ki) - °æÈñ´ëÇб³ ÀÇ°ú´ëÇÐ Ä¡·á¹æ»ç¼±°úÇб³½Ç
Abstract
1981³âºÎÅÍ 1989³â±îÁö °æÈñ´ëÇÐ ºÎ¼Óº´¿ø Ä¡·á¹æ»ç¼±°ú¿¡¼ ¹«±âÆó¸¦ µ¿¹ÝÇÑ Æó¾ÏÀ¸·Î ¹æ»ç¼± Ä¡·á¸¦ ¹ÞÀº ȯÀÚÁß, °ú°Å·Â»ó ÆóÀýÁ¦¼ú, Ç׾Ͽä¹ý, ¹æ»ç¼±Ä¡·áµîÀÇ ±â¿Õ·ÂÀÌ Àִ ȯÀÚ¸¦ Á¦¿ÜÇÑ 42¸íÀ» ´ë»óÀ¸·Î Ä¡·á¼ºÀûÀ» ºÐ¼®ÇÏ¿´´Ù.
1. ºñ¼Ò¼¼Æ÷¼º Æó¾ÏÀº 62% (21/34), ¼Ò¼¼Æ÷¼º Æó¾ÏÀº 75% (6/8)¿¡¼ °¢°¢ ¹«±âÆó°¡ ¹æ»ç¼± Ä¡·áÈÄ ÀçÆØ⠵ǾúÀ¸¸ç, Àüü ȯÀÚÀÇ 64% (27/42)¿¡¼ ºÎºÐ ¶Ç´Â ¿ÏÀü¹ÝÀÀ(reexpansion)À» ³ªÅ¸³»¾ú´Ù.
2. ¹æ»ç¼± ÃѼ±·®ÀÌ 40 Gy (1297 ret) ÀÌÇÏ¿Í 40 Gy (1337 ret) ÀÌ»óÀÎ ±º¿¡¼ ¹ÝÀÀÀº °¢°¢ 50% (6/12)¿Í 70% (21/30)À̾úÀ¸¸ç, ÃѼ±·®°ú ¹«±âÆó ¹ÝÀÀ»çÀÌ¿¡´Â À¯ÀÇÇÑ °ü°è°¡ ÀÖ¾ú´Ù(p<0.01).
3. ºÐÇÒÁ¶»ç¼±·®¿¡ µû¸¥ ¹ÝÀÀÀ²Àº ¼Ò¼±·®(180¡220 cGy)¿¡¼´Â 53% (14/22), ´ë¼±·®(300 cGy)¿¡¼´Â 65% (13/20)À̾ú´Ù.
4. ÀÌ»óÀÇ ¼ºÀûÀ¸·Î º¸¾Æ ¹«±âÆó¸¦ µ¿¹ÝÇÑ Æó¾Ï ȯÀÚÁß¿¡¼, ƯÈ÷ ¼ö¼ú°ú Ç׾Ͽä¹ýÀ¸·Î Ä¡·á°¡ °ï¶õÇÏ°í Á¶¼ÓÇÑ Ã³Ä¡¸¦ ¿äÇÏ´Â ºñ¼Ò¼¼Æ÷¼º Æó¾Ï¿¡¼ ¹æ»ç¼± Ä¡·áÀÇ Áß¿äÇÑ ¿ªÇÒÀÌ È®ÀεǾú´Ù.
From January 1981 to December 1989, total 42 patients with atelectasis from lung cancer were treated with radiation therapy at the Department of Therapeutic Radiology in Kyung Hee University Hospital. The reexpansion of atelectasis after radiotherapy of the lung was evaluated retrospectively, utilizing treatment records and follow-up chest radiographs. Of the patients with non-small cell carcinoma of the lung, the response rate was 62% (21/34). Patient with small cell carcinoma showed a 75% (6/8) response rate. There appears to be some evidence of a relationship of total tumor dose versus response of atelectasis; radiation dose over 40 Gy (1337 ret), had a favorable effect on the rate of response compared with that below 40 Gy (1297 ret), 70% (21/30) and 50% (6/12), respectively (p<0.01). Total response rate (partial and complete responses) of all patients was 64% (27/42). Franction size was not contributed to the difference of response rates between small fraction (180¡200 cGy) and large fraction (300 cGy), 53% (14/22) and 65% (13/20), respectively. The results of this study suggest that radiation therapy has a definite positive role in management of atelectasis caused by lung cancer, especially in inoperable non-small cell carcinoma.
Å°¿öµå
Radiation therapy, Lung cancer, Atelectasis
KMID :
0362919900080010073
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À¯È¿¼º°á°ú(Recomendation)
Radiation therapy has a definite positive role in management of atelectasis caused by lung cancer, especially in inoperable non-small cell carcinoma.